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Greek-American James A. Koshivos, 21, Killed after Car Plunged into Ocean
FALMOUTH, MA – The police in Falmouth have identified the victim in an accident involving a car plunging into the ocean on February 20, NBC10 Boston reported.
NEW YORK — New data indicate the COVID-19 vaccine developed by Pfizer and German partner BioNTech could be stored for two weeks without the ultracold storage currently required, potentially making its use a bit easier.
The companies said Friday they’ve submitted findings from ongoing stability testing to the U.S. Food and Drug Administration, which has authorized the vaccine’s emergency use in the U.S., and will send the data to regulators around the world in the next few weeks.
The companies want regulators to update temperature requirements to state the vaccines can maintain their potency for two weeks if kept at -13°F to 5°F (-25°C to -15°C), as an additional option.
Freezers and refrigerators used in many pharmacies and hospitals commonly chill to those temperatures — but not to the temperature range
currently authorized, from -112°F to -76°F (-80°C to -60°C). The vaccine can remain stable at those temperatures for up to six months.
That’s why New York-based Pfizer and BioNTech ship the vaccine vials in special thermal containers that can serve as temporary storage for up to 30 days by repeatedly adding dry ice. Still, that can make storing and then thawing and administering the two-dose vaccine challenging in many places, particularly developing countries.
The companies have been testing stability of vaccine batches manufactured at different times over the past nine months and continue to research ways to boost the vaccine’s “shelf life.”
“If approved, this new storage option would offer pharmacies and vaccination centers greater flexibility in how they manage their vaccine supply,” Pfizer Chief Executive Albert Bourla said in a statement.
The shot is one of just two vaccines that have emergency use authorization in the U.S., though a third vaccine, created by Johnson & Johnson, is expected to win FDA clearance for emergency use within two weeks.
The other vaccine now authorized in the U.S., made by Moderna, started out with similarly cold temperature requirements in early-stage studies before stability testing showed it could be stored at normal freezer temps.
We are continually working to make the Pfizer/BioNTech vaccine as accessible as possible. Today we shared new data demonstrating the stability of the vaccine when stored for 2 weeks at temps more commonly found in pharmaceutical freezers and refrigerators. https://t.co/irOQA2v08ppic.twitter.com/lZhpQctZJ0
— AlbertBourla (@AlbertBourla) February 19, 2021
FALMOUTH, MA – The police in Falmouth have identified the victim in an accident involving a car plunging into the ocean on February 20, NBC10 Boston reported.
A mother and her 14-year-old daughter are advocating for better protections for victims after AI-generated nude images of the teen and other female classmates were circulated at a high school in New Jersey.
KHAN YOUNIS, Gaza Strip (AP) — Israel's military on Sunday ordered more areas in and around Gaza's second-largest city of Khan Younis to evacuate, as it shifted its offensive to the southern half of the territory where it says many Hamas leaders are hiding.
CARACAS, Venezuela (AP) — Venezuelans are voting in a referendum Sunday to supposedly decide the future of a large swath of neighboring Guyana that their government claims ownership of, arguing the territory was stolen when a north-south border was drawn more than a century ago.
CEDAR RAPIDS, Iowa (AP) — Former President Donald Trump on Saturday attempted to turn the tables on his likely rival in November, President Joe Biden, arguing that the man whose election victory Trump tried to overturn is “the destroyer of American democracy.
NANTES, France (AP) — A supporter from Nantes died on Saturday following a fight that took place before the club's 1-0 win over Nice in the latest outbreak of violence to mar French soccer this season.